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Some drugs other than chemotherapy can suppress platelet production, such as thiazide diuretics. Cancers of the bone marrow and blood (leukemia) or cancers of the lym ph nodes (lymphoma) can cause various degrees of thrombocytopenia. Cancers from other organs can sometimes infiltrate (invade) the bone marrow and result in impaired production of platelets. Long term alcohol can cause direct toxicity of the bone marrow. Deficiency of vitamin B12 and folic acid can result in low platelet production by the bone marrow.

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Retrieved August 12, 2015.

Individuals with certain variants of the trait may survive and reproduce more than individuals with other, less successful, variants, therefore, factors that affect reproductive success are also important, including sexual selection and fecundity selection. Over time, this process can result in populations that specialise for particular ecological niches, in other words, natural selection is a key process in the evolution of a population. Natural selection can be contrasted with artificial selection, in which humans intentionally choose specific traits, Natural selection is one of the cornerstones of modern biology.

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